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Accessibility and affordability

Accessibility

Focus on underserved treatment areas 
Orexo targets opioid use disorder (OUD), a long-overlooked treatment area, through the products Zubsolv® and MODIA®.

Healthcare provider education
Orexo combats stigma by educating healthcare providers (HCPs) and the public about OUD as a medical condition. In 2024, its sales team engaged in over 42,000 educational interactions with HCPs.

Patient and provider support 
The MATCore® program integrates Orexo’s OUD treatment portfolio with education and outreach to reach even the most marginalized populations.

Product innovation
Orexo is expanding its treatment options, including OX124, a high-dose naloxone rescue medication for opioid overdoses. Although delayed due to regulatory requirements coupled to commercial manufacturing, it addresses an unmet need.

The next-generation formulation technology, AmorphOX®, enhances the chemical and physical stability of substances that typically degrade over time. This improved stability can reduce logistical complexity by eliminating the need for cold chain storage, ultimately contributing to reach more patients through more efficient and resilient supply chains.

Affordability

Offering patient assistant programs 
To reach financial vulnerable individuals, Orexo provides three patient assistant programs. These programs are

    • Income-based assistance (covers full costs)
    • Co-pay assistance (covers up to USD 225 per prescription)
    • 15-tablet voucher program (two free tablet vouchers to cover gap between diagnosis and insurance approval).

Medicaid reimbursement progress
Medicaid coverage for Zubsolv® has grown from 30% to 50% during the last years, expanding access for lower-income patients.

Private insurance coverage: 98% of privately insured patients are eligible for reimbursement, demonstrating strong financial accessibility.